LGD-4033 (Ligandrol) Review

Is LGD-4033 safe for health? Does it give better gains than steroids? Or maybe instead of promised benefits, it causes cancer?
We will answer these and other questions in this article below.

What is LGD-4033 (Ligandrol)?

sarm lgd 4033 capsules

LGD-4033 also known as Ligandrol and Anabolicum is a selective androgen receptor modulator (SARM). These substances stimulate only androgen receptors found in muscles and bones, thus avoiding side effects of steroids or prohormones, which also affect the heart, prostate, hair and sebaceous glands.


LGD-4033 is one of the most popular SARMs on the market. Developed by Ligand Pharmaceuticals to prevent such diseases as muscle atrophy or osteoporosis, quickly gained popularity among athletes as a result of its ability to quickly build lean body mass. To illustrate how popular this drug is – Joakim Noah, the basketball player and Florida Gators’ quarterback Will Grier, who claims to have gained a weight of 43lb (20kg) in a year with Ligandrol, were caught on this kind of legal “doping”. 


Excellent results are also confirmed by studies. In the first clinical trials, people taking only 1mg of LGD-4033 daily recorded a 1.2kg increase in muscle mass over 21 days. . Note that the standard dose used in bodybuilding is 10mg per day. 


Benefits of LGD-4033

  • Rapid muscle mass gain – LGD 4033 is one of the strongest legal anabolic agents currently available on the market. It allows to gain 3-5 kg of muscle mass during 6-8 weeks of solo use. Effects may be amplified by using LGD in combination with other SARMs. It is also worth noting that, in contrary to steroids, SARM users retain practically 100% of the muscles built on the cycle.
  • Loss of fat tissue – although Ligandrol does not directly burn fat, it accelerates metabolism and muscle fiber synthesis, which can result in the loss of a few pounds of fat during a long cycle.
  • Strength increase – Ligandrol is a great substance to break your records and break stagnation. It increases the production of red blood cells and thus the blood supply to the muscle tissue. The highest increases in strength are observed after about 3 weeks of use.
  • Faster regeneration – while using Ligandrol you can increase the workout load by 30-40% without worrying about overtraining. 
  • “Pump” – During the LGD cycle your muscles will be more loaded with water and thus visually bigger and harder. The number of visible veins will also increase. The effects are similar to those of Anavar or Dianabol.
  • Increased libido – unfortunately, this is not the effect experienced by all LGD users. However, a significant number of users claim that their libido has improved significantly since week 2 of the cycle.
  • Increasing bone density is a change that you will not notice with the naked eye. However, research shows that Ligandrol can increase bone density by 6.4% on average within 3 months. This is a particularly important effect for people who have recently fractured or suffer from bone diseases. 

Side effects

You’re probably wondering if such a strong anabolic agent has any side effects. The information gathered from users and studies conducted so far suggests that LGD-4033 has no significant side effects. 

Steroid-specific side effects such as gynaecomastia, acne, hair loss, hepatotoxicity, prostate problems, high blood pressure and cardiovascular problems do NOT apply to SARMs. 

Unfortunately, there are many products on the market that are contaminated with oral anabolic steroids or prohormones. Such products may cause the above mentioned symptoms. For this reason, SARMs should only be purchased from reliable sources that have a certificate of analysis for each batch. 

PCT (Post Cycle therapy) LGD-4033

As we mentioned in other articles, long cycles (>8 weeks or in combination with other SARMs) of Ligandrol can cause testosterone suppression of 30-60%. However, opinions on whether PCTs should be used after a cycle with LGD-4033 are mixed. 

On the one hand, since SARMs have only a minor impact on HPTA, testosterone levels should return to precycle levels on their own within about two weeks. 

On the other hand, during this time, you may feel unwell and lose some gains from the cycle. 

Taking into account the feedback from gym friends and the ones found on the Internet, I do not think that PCT is necessary. Of course, if you have Clomid or Novalex on hand it is worth throwing them in a week or two before the end of the cycle to improve your mood and maintain 100% of the muscles gained. But even without these drugs testosterone should return to normal values in no time

LGD-4033 Dosage

Ligandrol has a half-life of more than 24 hours, so it can be administered once a day. Our suggested dose is 10-20 mg per day for 6 to 8 weeks.

LGD gives great results in combination with other SARMs. If you want to quickly gain muscle mass it is advisable to combine it with RAD-140 in the dose of 5mg and/or MK-677 in the dose of 20mg. 

While cutting the best results will be achieved in combination with GW-501516 in 10-20mg dose or MK-2866 in 30mg dose.

Before and after LGD-4033 

My personal experience with LGD-4033

I started my adventure with SARMs about 5 years ago when I had to stop steroids because my wife and I were planning to have a baby. During this period I was on 4-5 cycles solo or part of which was LGD-4033.

I could compare my first cycle of LGD-4033 to a small dose of testosterone enanthate (~300-350mg/week). I took 20 mg daily for 8 weeks. In the 6th week I turned on Nolvadex preventively, as I still have a dozen or so packages, so it’s hard for me to say if there was a significant testosterone suppression. In case of people who do not have PCT at hand I would suggest to start with 10mg per day in combination with other SARM.

Personally, I think SARMs are a great alternative for people who for some reason do not want or cannot use anabolic steroids. They provide excellent results – certainly much better than any supplements on the market, without any significant side effects. 

Stacking Ligandrol with other SARMs


In my career I have tested a dozen or so different sarm combinations. As far as buking is concerned, I have developed 3 reliable stacks. I will present here 2 of them that are based on LGD-4033. 

LGD-403310mgweek 1-6
RAD-14010mgweek 1-6

It is an ideal stack for beginners who want to start their journey with SARMs. These are two agents with the greatest anabolic potential, giving rapid growth of lean mass. If you have already tried any of these substances, you know how strong they can be on their own. This combination will give you even better results as most of the SARMs work synergistically with each other.

If you need a very fast weight gain and you have a little more money, you can try a more advanced cycle.

LGD-403310mg1-8 week
MK-67710mg1-8 week
S2310mg1-8 week

This is the best combination for a typical mass I’ve ever had a chance to try. It delivers the greatest gains of all tested stacks. Each of these substances affects different receptors, causing a simultaneous increase in mass, strength, pump and regeneration.


Cutting on LGD-4033 is often more like a recomposition. To speed up fat loss we can include Ostarine or GW-501516. Both of these substances significantly accelerate metabolism and improve physical condition. Not only will they increase your daily energy requirement, but also allow you to have longer cardio sessions. At the same time LGD-4033 will stop catabolism and allow to preserve most of your muscles.  

LGD-40335mgweek 1-10
MK-286620mgweek 1-10
GW-150151610mgweek 1-10

Personally, on this stack I managed to decrease the level of fat tissue by 5% within 10 weeks, at the same time increasing the lean body weight. During this period I did not experience any side effects – except maybe for the reduced libido. However, I suspect that this was a result of high calorie restrictions and too little fat in my diet.

Where to buy lgd-4033?

Unfortunately, most of the SARMs present on the American market have hardly anything in common with their names. Most of the recently tested products had only a negligible amount of the declared substance. Moreover, it is a common practice among manufacturers to add prohormones and steroids. For this reason, you should buy SARMs only from reliable suppliers – they should preferably have a Certificate of Analysis (CoA) issued by an external laboratory for each batch sold. 

Stores we recommend

Proven peptides

proven peptides logo

Currently one of the most trusted shops in the world. Proven peptides offer SARMs exclusively in the form of solutions. Each bottle is accompanied by a pipette and information on the amount of agent equivalent to 1ml. Each product also has a separate analysis certificate issued by an external laboratory.
The store offers a loyalty program “Peptide Points” in which collected points reduce the cost of future orders. There is a contact phone on the website, so you can get an answer to all your questions within a few minutes. Shipping from the USA.

Click here to check price


chemyo logo

Relatively young shop, but rapidly gaining in popularity. This is due to very attractive prices in comparison with the competition and high transparency of the shop. The analysis certificates for each product can be downloaded directly from the website.
Like Proven Peptides, they offer SARMs only in the form of solutions. However, the bottle does not include a pipette (you can buy a 1ml syringe for $1 on the website). Shipping from the USA.

Click here to check price


swisschems logo

The youngest shop on the list, not very popular at the moment. Unlike its predecessors, it offers SARMs in capsule and injection form. Apart from SARMs, the store also offers PCT agents, aromatase inhibitors, agents for erection problems, peptides and nootropes. Shipping from the USA

Click here to check price


Although for a very long time SARMS4YOU was our favourite vendor, we are forced to change our recommendation. In recent months, contact with them is difficult, packages come out even with a 2-3 week delay, and quality has significantly decreased.
I apologize in advance to those who bought SARMs from this store based on my recommendation, before updating this review.

Frequently Asked Questions

When to take Ligandrol? 

It is best to take LGD 4033 in the morning before the first meal. 

How to use LGD 4033 in the form of a solution?

On the packaging you will find information on how much mg of the agent is in a drop of solution. In case of water-soluble agents, sprinkle a sufficient amount of solution into a glass of juice/water/tea. For SARMs dissolved in oil, sprinkle it directly into your mouth or onto a small piece of bread. 

How long is it possible to detect LAGs in the body?

Metabolites of LGD are detectable in the body for about 21 days after discontinuation. 

How many times a week do you train at 4033 lgd?

There is no clear answer to this question because every body is different.

During a cycle of LGD-4033 in 2-3rd week there should be an increase in strength and weight. This means that a sufficient amount of the agent has accumulated in the body. Since then we can usually add 1 hard or 2 light workouts a week to the work we have been doing so far. 

When will I see the first results?

The first results can be seen after just a few days of using LGD-4033. This includes mainly improved mood and increased libido.  The biggest changes are observed in the 2nd or 3rd week of use when there is a dramatic increase in strength and mass. 

What results can I expect from the first cycle of LGD-4033? 

The effects depend on many factors – diet, workout quality, quantity and length of the product used and whether it was used alone or in combination with other SARMs. 

However, if you are far from your natural maximum, you can expect an increase of 3-5kg of lean body weight within 6-8 weeks of using 10mg per day.

Does Ligandrol cause acne?

In most cases, LGD has no effect on acne. 

Does Ligandrol cause hair loss?

There is no evidence to suggest that Ligandrol has an effect on hair loss.

Which sarm is better lgd 4033 vs. Radi140?

Both of these substances can provide excellent results, however, RAD-140 is SARM with greater anabolic strength than LGD-4033. 

Which SARM is better: Ostarine vs. Ligandrol

Ligandrol will do better on the “mass” and Ostarin will do better   during cutting

What is Ligandrol half-life?

LGD-4033 has a 30-hour half-life time.

Is it legal?

LGD-4033 is legal in most countries of the world, including United States of America. However, it is on the WADA list and therefore cannot be used by professionals.